PRIMARY RESEARCH | PUBMED LINKS
DRUG CATEGORY: PEPTIDES+ (ANTI-AGING)
DRUG NAME: METHYLENE BLUE

  • FDA Safety Data Sheet not available

  • Xue H. The Potentials of Methylene Blue as an Anti-Aging Drug. Cells. 2021 [PubMed Link]

  • Liu Y. Customized Intranasal Hydrogel Delivering Methylene Blue Ameliorates Cognitive Dysfunction against Alzheimer's Disease. Adv Mater. 2024 [PubMed Link]

  • Xiong ZM. Anti-Aging Potentials of Methylene Blue for Human Skin Longevity. Sci Rep. 2017 [PubMed Link]

  • Tucker D. From Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene Blue. Mol Neurobiol. 2018 [PubMed Link]

  • Hashmi MU. Exploring Methylene Blue and Its Derivatives in Alzheimer's Treatment: A Comprehensive Review of Randomized Control Trials. Cureus. 2023 [PubMed Link]

  • Nair A. Using intravenous methylene blue to reduce postoperative cognitive disorders in elderly patients - a methodical approach. J Clin Anesth. 2021 [PubMed Link]

  • Méndez M. Methylene blue and photobiomodulation recover cognitive impairment in hepatic encephalopathy through different effects on cytochrome c-oxidase. Behav Brain Res. 2021 [PubMed Link]

  • Deng Y. Methylene blue reduces incidence of early postoperative cognitive disorders in elderly patients undergoing major non-cardiac surgery: An open-label randomized controlled clinical trial. J Clin Anesth. 2021 [PubMed Link]

  • Auchter A. Therapeutic benefits of methylene blue on cognitive impairment during chronic cerebral hypoperfusion. J Alzheimers Dis. 2014 [PubMed Link]

  • Krutskikh EP. Brain Protection by Methylene Blue and Its Derivative, Azur B, via Activation of the Nrf2/ARE Pathway in Cisplatin-Induced Cognitive Impairment. Pharmaceuticals (Basel). 2022 [PubMed Link]

  • Oz M, Lorke DE. Methylene blue and Alzheimer's disease. Biochem Pharmacol. 2009 [PubMed Link]

  • Wiklund L. Neuroprotection by Methylene Blue in Cerebral Global Ischemic Injury Induced Blood-Brain Barrier Disruption and Brain Pathology: A Review. CNS Neurol Disord Drug Targets. 2016 [PubMed Link]

  • Shen J. Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury. Front Neurol. 2019 [PubMed Link]