PRIMARY RESEARCH | PUBMED LINKS
DRUG CATEGORY: PEPTIDES+ (SKIN + HAIR)
DRUG NAME: LL-37 SKIN

  • FDA Safety Data Sheet not available (experimental peptide).

  • Vandamme D. A comprehensive summary of LL-37, the factotum human cathelicidin peptide. Cell Immunol. 2012 [PubMed Link]

  • van der Does AM. Induction of the human cathelicidin LL-37 as a novel treatment against bacterial infections. J Leukoc Biol. 2012 [PubMed Link]

  • Nijnik A. The roles of cathelicidin LL-37 in immune defences and novel clinical applications. Curr Opin Hematol. 2009 [PubMed Link]

  • Kahlenberg JM. Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J Immunol. 2013 [PubMed Link]

  • Chen K. The potentials of short fragments of human anti-microbial peptide LL-37 as a novel therapeutic modality for diseases. Front Biosci (Landmark Ed). 2021[PubMed Link]

  • Alexandre-Ramos DS. LL-37 treatment on human peripheral blood mononuclear cells modulates immune response and promotes regulatory T-cells generation. Biomed Pharmacother. 2018 [PubMed Link]

  • Tjabringa GS. The human cathelicidin LL-37: a multifunctional peptide involved in infection and inflammation in the lung. Pulm Pharmacol Ther. 2005 [PubMed Link]

  • Wang G. Design of Antimicrobial Peptides: Progress Made with Human Cathelicidin LL-37. Adv Exp Med Biol. 2019 [PubMed Link]

  • Acen EL. Impact of vitamin D status and cathelicidin antimicrobial peptide on adults with active pulmonary TB globally: A systematic review and meta-analysis. PLoS One. 2021 [PubMed Link]

  • Ho J. Pathological Role and Diagnostic Value of Endogenous Host Defense Peptides in Adult and Neonatal Sepsis: A Systematic Review. Shock. 2017 [PubMed Link]

  • Aloul KM. Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis. Front Immunol. 2022 [PubMed Link]

  • Piktel E. The Role of Cathelicidin LL-37 in Cancer Development. Arch Immunol Ther Exp (Warsz). 2016 [PubMed Link]

  • Sánchez-Peña FJ, Romero-Tlalolini MLÁ, Torres-Aguilar H, et al. LL-37 Triggers Antimicrobial Activity in Human Platelets. Int J Mol Sci. 2023 [PubMed Link]