PRIMARY RESEARCH | PUBMED LINKS
DRUG CATEGORY: PEPTIDES+ (TISSUE RECOVERY)
DRUG NAME: THYMOSIN BETA-4

  • FDA Safety Data Sheet not available (experimental peptide therapy)

  • Esposito S. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500, a product suspected to possess doping potential. Drug Test Anal. 2012 [PubMed Link]

  • Sosne G. Thymosin beta 4: A potential novel adjunct treatment for bacterial keratitis. Int Immunopharmacol. 2023 [PubMed Link]

  • Bako P. Thymosin beta-4 - A potential tool in healing middle ear lesions in adult mammals. Int Immunopharmacol. 2023 [PubMed Link]

  • Bock-Marquette. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies. Int Immunopharmacol. 2023 [PubMed Link]

  • Xing Y. Progress on the Function and Application of Thymosin β4. Front Endocrinol (Lausanne). 2021 [PubMed Link]

  • Gonzalez-Franquesa A. Discovery of thymosin β4 as a human exerkine and growth factor. Am J Physiol Cell Physiol. 2021 [PubMed Link]

  • Wang X. A first-in-human, randomized, double-blind, single- and multiple-dose, phase I study of recombinant human thymosin β4 in healthy Chinese volunteers. J Cell Mol Med. 2021 [PubMed Link]

  • Tian Z. Thymosin β4 Suppresses LPS-Induced Murine Lung Fibrosis by Attenuating Oxidative Injury and Alleviating Inflammation. Inflammation. 2022 [PubMed Link]

  • Yu R. Recombinant human thymosin beta-4 (rhTβ4) improved scalp condition and microbiome homeostasis in seborrheic dermatitis. Microb Biotechnol. 2021 [PubMed Link]

  • Maar K. Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State-New Directions in Anti-Aging Regenerative Therapies. Cells. 2021 [PubMed Link]

  • Lv S. Thymosin‑β 4 induces angiogenesis in critical limb ischemia mice via regulating Notch/NF‑κB pathway. Int J Mol Med. 2020 [PubMed Link]

  • Song K. Thymosin beta 4 attenuates PrP(106-126)-induced human brain endothelial cells dysfunction. Eur J Pharmacol. 2020 [PubMed Link]

  • Pipes GT. Cardioprotection by Thymosin Beta 4. Vitam Horm. 2016 [PubMed Link]

  • Ho JH. Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage. Br J Ophthalmol. 2008 [PubMed Link]